Cardiomyocyte Cell-Cycle Activity during Preadolescence

Affiliations

¹ The Krannert Institute of Cardiology, and the Riley Heart Research Center, Wells Center for Pediatric Research, and Indiana University School of Medicine, 1044 West Walnut Street, Indianapolis, IN 46202, USA.
² Experimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 12, 91054, Erlangen, Germany.
³ The Cardiovascular Division of the Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
⁴ The Krannert Institute of Cardiology, and the Riley Heart Research Center, Wells Center for Pediatric Research, and Indiana University School of Medicine, 1044 West Walnut Street, Indianapolis, IN 46202, USA. Electronic address: ljfield@iupui.edu.

Free article

Comment

Mark H Soonpaa et al. Cell. 2015.

Free article

. 2015 Nov 5;163(4):781-2.

doi: 10.1016/j.cell.2015.10.037.

¹ The Krannert Institute of Cardiology, and the Riley Heart Research Center, Wells Center for Pediatric Research, and Indiana University School of Medicine, 1044 West Walnut Street, Indianapolis, IN 46202, USA.
² Experimental Renal and Cardiovascular Research, Department of Nephropathology, Institute of Pathology, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Schwabachanlage 12, 91054, Erlangen, Germany.
³ The Cardiovascular Division of the Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA 02215, USA.
⁴ The Krannert Institute of Cardiology, and the Riley Heart Research Center, Wells Center for Pediatric Research, and Indiana University School of Medicine, 1044 West Walnut Street, Indianapolis, IN 46202, USA. Electronic address: ljfield@iupui.edu.

No abstract available

Comment in

Cardiomyocytes Replicate and their Numbers Increase in Young Hearts.
Naqvi N, Singh R, Iismaa SE, Li M, Calvert JW, Martin DI, Harvey RP, Graham RM, Husain A. Naqvi N, et al. Cell. 2015 Nov 5;163(4):783-4. doi: 10.1016/j.cell.2015.10.038. Cell. 2015. PMID: 26544928 Free PMC article. No abstract available.

A proliferative burst during preadolescence establishes the final cardiomyocyte number.
Naqvi N, Li M, Calvert JW, Tejada T, Lambert JP, Wu J, Kesteven SH, Holman SR, Matsuda T, Lovelock JD, Howard WW, Iismaa SE, Chan AY, Crawford BH, Wagner MB, Martin DI, Lefer DJ, Graham RM, Husain A. Naqvi N, et al. Cell. 2014 May 8;157(4):795-807. doi: 10.1016/j.cell.2014.03.035. Cell. 2014. PMID: 24813607 Free PMC article.