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Review
. 1989 Jan;3(1):119-24.
doi: 10.1111/j.1365-2958.1989.tb00111.x.

Genetics of pertussis toxin

R Gross  1 , B Aricò, R Rappuoli
Affiliations
Review

Genetics of pertussis toxin

R Gross et al. Mol Microbiol. 1989 Jan.

Abstract

Pertussis toxin (PT) is the major virulence factor of Bordetella pertussis. The cloning and nucleotide sequencing of the PT genes from B. pertussis, Bordetella parapertussis and Bordetella bronchiseptica has elucidated the evolution of the Bordetella species and allowed considerable advances towards the understanding of their gene expression and the development of safer vaccines against pertussis.

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