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. 2016 Jan-Feb;27(1):5-16.
doi: 10.1016/j.jana.2015.10.002. Epub 2015 Oct 13.

Sleep, Fatigue, and Problems With Cognitive Function in Adults Living With HIV

Eeeseung Byun, Caryl L Gay, Kathryn A Lee

Sleep, Fatigue, and Problems With Cognitive Function in Adults Living With HIV

Eeeseung Byun et al. J Assoc Nurses AIDS Care. 2016 Jan-Feb.

Abstract

Up to 50% of people living with HIV have some neurocognitive impairment. We examined associations of sleep and fatigue with self-reported cognitive problems in 268 adults living with HIV. Multivariate regression was used to examine associations between cognitive problems, self-reported sleep quality, actigraphy-measured total sleep time and wake after sleep onset, and fatigue severity. Poorer self-reported sleep quality (p < .001), short or long total sleep time (<7 or >8 vs. 7-8 hours, p = .015), and greater fatigue (p < .001) were associated with lower self-reported cognitive function scores after controlling for demographic and clinical characteristics. However, objective measure of wake after sleep onset was unrelated to self-reported cognitive function scores. Findings suggest that assessing and treating poor sleep and complaints about fatigue would be areas for intervention that could have a greater impact on improving cognition function than interventions that target only cognitive problems.

Keywords: HIV; cognition; fatigue; sleep.

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Conflict of interest statement

Disclosures

The authors report no real or perceived vested interests that relate to this article that could be construed as a conflict of interest.

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