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Review
. 2016 Feb:85:86-93.
doi: 10.1016/j.jinsphys.2015.11.005. Epub 2015 Nov 5.

Diet-delivered RNAi in Helicoverpa armigera--Progresses and challenges

Zhi Xian Lim  1 , Karl E Robinson  1 , Ritesh G Jain  1 , G Sharath Chandra  2 , R Asokan  2 , Sassan Asgari  3 , Neena Mitter  4
Affiliations
Review

Diet-delivered RNAi in Helicoverpa armigera--Progresses and challenges

Zhi Xian Lim et al. J Insect Physiol. 2016 Feb.

Abstract

Helicoverpa armigera (the cotton bollworm) is a significant agricultural pest endemic to Afro-Eurasia and Oceania. Gene suppression via RNA interference (RNAi) presents a potential avenue for management of the pest, which is highly resistant to traditional insecticide sprays. This article reviews current understanding on the fate of ingested double-stranded RNA in H. armigera. Existing in vivo studies on diet-delivered RNAi and their effects are summarized and followed by a discussion on the factors and hurdles affecting the efficacy of diet-delivered RNAi in H. armigera.

Keywords: Cotton bollworm; Diet-delivery; Helicoverpa armigera; RNA interference; RNAi; dsRNA uptake.

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