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. 2015 Aug 15;8(8):13403-7.
eCollection 2015.

Surgical treatment for a paraplegic patient induced by congenital factor X deficiency

Weicheng Lin  1 , Jing Zhou  1 , Tianbing Wang  1 , Peixun Zhang  1
Affiliations

Surgical treatment for a paraplegic patient induced by congenital factor X deficiency

Weicheng Lin et al. Int J Clin Exp Med. .

Abstract

Congenital factor X (FX) deficiency is a rare disease which usually leads to coagulation disorders. We reported a case of paraplegic patient induced by traumatic spinal epidural hematoma which was associated with congenital FX deficiency. The treatments of this patient included elevating FX activity (FX: C) by adding fresh-frozen plasma (FFP) or prothrombin complex concentration (PCC) to improve his coagulation function, and doing operation to remove his spinal hematoma. Symptoms started to resolve after operation. Besides, we found one of his elder brother had the same disease as the patient himself via family follow-up. They can survive because their FX: C are relatively high enough to keep them away from fatal bleeding.

Keywords: Congenital factor X deficiency; spinal epidural hematoma.

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Figures

Figure 1
Figure 1
Preoperative lumbar MRI (saggital plane, t2 imaging) showing a hematoma in the spinal canal at the T10-L1 level.
Figure 2
Figure 2
Preoperative lumbar MRI (saggital plane, t1 imaging) showing a hematoma in the spinal canal at the T10-L1 level.
Figure 3
Figure 3
Preoperative lumbar MRI (axial plane, t2 imaging) showing a hematoma at the posterior surface of spinal cord.
See this image and copyright information in PMC

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