[The structure of eukaryotic genes]

Abstract

The structure of eukaryotic transcription units and already known DNA elements which influence gene expression and eukaryotic gene regulation are described. In recent years molecular genetics approaches have been used to identify and characterize the molecular anatomy of protein-coding eukaryotic genes. Within these genes there are modular sequences, consisting of arrays of short, highly conserved recognition elements that are essential for the initiation of transcription, translation, and tissue-specificity of gene expression. The skillful combination of promoters, enhancers and other regulatory sequences allows the expression of every gene in every organ or tissue of a transgenic animal.