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Review
. 2016 May;101(5):475-80.
doi: 10.1136/archdischild-2014-307217. Epub 2015 Nov 9.

Management of Crohn's disease

Jochen Kammermeier  1 , Mary-Anne Morris  2 , Vikki Garrick  3 , Mark Furman  4 , Astor Rodrigues  5 , Richard K Russell  3 ; BSPGHAN IBD Working Group
Collaborators, Affiliations
Review

Management of Crohn's disease

Jochen Kammermeier et al. Arch Dis Child. 2016 May.

Abstract

Crohn's disease (CD) is rapidly increasing in children so an up to date knowledge of diagnosis, investigation and management is essential. Exclusive enteral nutrition is the first line treatment for active disease. The vast majority of children will need immunosuppressant treatment and around 20% will need treatment with biologics. Recent guidelines have helped make best use of available therapies.

Keywords: Gastroenterology; Therapeutics.

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Figures

Figure 1
Figure 1
(A) Left: endoscopic view of the transverse colon in Crohn’s disease (CD) revealing a cluster of deep ulcers. (B) Centre: magnetic resonance enterography showing extensive terminal ileal disease. (C) Right: perianal disease (inflamed skin tag and external orifice of a fistula at 10:00) in CD patient (reproduced with permission).
Figure 2
Figure 2
Diagnostic pathways in Crohn’s disease (CD). Patients displaying features, consistent with CD should be fast tracked for specialist review. IBD, inflammatory bowel disease; MRE, magnetic resonance enterography; VCE, video capsule endoscopy.
See this image and copyright information in PMC

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