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. 2013:2013:907525.
doi: 10.1155/2013/907525. Epub 2013 Jan 17.

Synthesis, Characterization, and Anti-Inflammatory Activity of Newer Quinazolinone Analogs

Chatrasal Singh Rajput  1 , Shiwani Singhal  2
Affiliations

Synthesis, Characterization, and Anti-Inflammatory Activity of Newer Quinazolinone Analogs

Chatrasal Singh Rajput et al. J Pharm (Cairo). 2013.

Abstract

A series of 3-[2'-(Substitutedbenzylideneamino)phenyl]-2-methyl-6-substituted quinazolin-4-ones (5-10), 3-[2'-(3(″)-chloro-2(″)-oxo-4(″)-substitutedphenylazetidin-1(″)-yl)phenyl]-2-methyl-6-substitutedquinazolin-4-ones (11-16), and 3-[2'-(2(″)-substitutedphenyl-4(″)-oxo-1(″),3(″)-thiazolidin-3(″)-yl)phentl]-2-methyl-6-substitutedquinazolin-4-ones (17-22) have been synthesized in the present study. The structures of the synthesized compounds were assigned on the basis of elemental analysis, IR, (1)H NMR, and mass spectral data. All the newly synthesized compounds were screened for anti-inflammatory and analgesic activities.

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