Koebner Phenomenon and Mycosis Fungoides
- PMID: 26557075
- PMCID: PMC4637793
- DOI: 10.1159/000440856
Koebner Phenomenon and Mycosis Fungoides
Abstract
Mycosis fungoides (MF) is the most frequent type of primary cutaneous T-cell/NK-cell lymphoma. The Koebner phenomenon is defined as the appearance of cutaneous lesions on previously noninvolved skin following trauma and is observed in a series of cutaneous diseases including psoriasis, lichen planus, viral warts, molluscum contagiosum, etc. In this case report, 3 patients with longstanding MF are presented, the 1st with the appearance of a circumscribed early-stage type MF lesion rapidly following a surgical excision of an infundibular cyst, the 2nd with the appearance of a unique unilateral palmar tumoral MF lesion at the pressure site of a crutch, and the 3rd presented localized MF early stage lesions at the friction site of a belt. This report suggests that some MF patients may experience Koebner phenomenon-induced MF lesions and that MF should be added to the long list of skin diseases potentially exhibiting the Koebner phenomenon.
Keywords: Isomorphic effect; Koebnerization; Mycosis fungoides; Primary cutaneous T-cell/NK-cell lymphoma; Traumatism.
Figures
Similar articles
-
Coexistence of Anogenital Psoriasis and Genital Warts - Is There an Optimal Treatment?Acta Dermatovenerol Croat. 2019 Dec;27(4):270-272. Acta Dermatovenerol Croat. 2019. PMID: 31969241
-
Primary cutaneous T-cell lymphoma (mycosis fungoides and Sézary syndrome): part I. Diagnosis: clinical and histopathologic features and new molecular and biologic markers.J Am Acad Dermatol. 2014 Feb;70(2):205.e1-16; quiz 221-2. doi: 10.1016/j.jaad.2013.07.049. J Am Acad Dermatol. 2014. PMID: 24438969 Review.
-
Lichen Sclerosus on the Sites of Striae Distensae and a Surgical Scar in a Patient with Coexistent Morphea.Acta Dermatovenerol Croat. 2019 Mar;27(1):44-46. Acta Dermatovenerol Croat. 2019. PMID: 31032793
-
Clindamycin-induced Maculopapular Exanthema with Preferential Involvement of Striae Distensae: A Koebner phenomenon?Acta Dermatovenerol Croat. 2018 Apr;26(1):61-63. Acta Dermatovenerol Croat. 2018. PMID: 29782303 Review.
-
Risk Factors for Skin Infections in Mycosis Fungoides.Dermatology. 2016;232(6):731-737. doi: 10.1159/000455944. Epub 2017 Mar 2. Dermatology. 2016. PMID: 28249285
Cited by
-
Eruptive Seborrheic Keratoses Restricted to Plaque/Patch-Stage Mycosis Fungoides.Case Rep Dermatol. 2017 Jun 8;9(2):35-39. doi: 10.1159/000471787. eCollection 2017 May-Aug. Case Rep Dermatol. 2017. PMID: 28690516 Free PMC article.
-
Clinical Diagnosis and Novel Treatment of Eyelid Molluscum Contagiosum.Case Rep Infect Dis. 2025 Apr 28;2025:9730930. doi: 10.1155/crdi/9730930. eCollection 2025. Case Rep Infect Dis. 2025. PMID: 40331104 Free PMC article.
-
Koebner phenomenon leading to the formation of new psoriatic lesions: evidences and mechanisms.Biosci Rep. 2019 Dec 20;39(12):BSR20193266. doi: 10.1042/BSR20193266. Biosci Rep. 2019. PMID: 31710084 Free PMC article. Review.
-
Clinical characteristics of Mycosis fungoides palmaris et plantaris: two cases and a systematic literature review.Eur J Dermatol. 2022 May 1;32(3):421-423. doi: 10.1684/ejd.2021.4126. Eur J Dermatol. 2022. PMID: 36065530 Free PMC article. No abstract available.
-
Dorsal Hand and Foot Mycosis Fungoides: Looking Beyond Mycosis Fungoides Palmaris et Plantaris.Acta Derm Venereol. 2022 Sep 28;102:adv00783. doi: 10.2340/actadv.v102.2557. Acta Derm Venereol. 2022. PMID: 36129248 Free PMC article. No abstract available.
References
-
- Kuner N, Hartschuh W, Khan-Durani B. Heinrich Köbner and the ‘isomorphic phenomenon’. History and review of the literature. Hautarzt. 2003;54:274–278. - PubMed
-
- Weiss G, Shemer A, Trau H. The Koebner phenomenon: review of the literature. J Eur Acad Dermatol Venereol. 2002;16:241–248. - PubMed
-
- Sagi L, Trau H. The Koebner phenomenon. Clin Dermatol. 2011;29:231–236. - PubMed
-
- Boyd AS, Neldner KH. The isomorphic response of Koebner. Int J Dermatol. 1990;29:401–410. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources