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. 2016 Jan 2;30(1):153-6.
doi: 10.1097/QAD.0000000000000942.

High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy

Chris P Eades  1 , Sophie A Herbert, Simon G Edwards, Laura J Waters, Tabitha Peake, Robert F Miller, Eva Jungmann
Affiliations

High rate of lymphoma among a UK cohort of adolescents with vertically acquired HIV-1 infection transitioning to adult care in the era of antiretroviral therapy

Chris P Eades et al. AIDS. .

Abstract

Among an inner London UK cohort of 147 adolescents transitioning from paediatric into adult care between 2007 and 2015, a new diagnosis of lymphoma was made in five patients; incidence rate = 0.425/100 person-years (95% confidence interval = 0.424-0.426). Previously described risk factors, including low nadir CD4 cell count and ongoing HIV-1 viraemia, appeared to be important. These data suggest that careful surveillance and a low threshold for investigating relevant symptoms continue to be essential for such patients.

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