Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Mar;74(3):966-70.
doi: 10.1073/pnas.74.3.966.

Minimal length of the lactose operator sequence for the specific recognition by the lactose repressor

C P Bahl, R Wu, J Stawinsky, S A Narang

Minimal length of the lactose operator sequence for the specific recognition by the lactose repressor

C P Bahl et al. Proc Natl Acad Sci U S A. 1977 Mar.

Abstract

A number of specific duplex DNA sequences which correspond to varying lengths of the lactose operator region have been synthesized by a combination of chemical and enzymatic methods. Repressor binding studies on these synthetic duplex operator molecules show that all the nucleotides essential for full lactose operator-repressor interactions are included in a 17-nucleotide-long duplex DNA that constitutes the minimal recognition sequence for this DNA-protein interaction.

PubMed Disclaimer

References

    1. J Biol Chem. 1975 Jun 25;250(12):4592-600 - PubMed
    1. J Am Chem Soc. 1975 Dec 10;97(25):7332-7 - PubMed
    1. Nature. 1976 Mar 25;260(5549):360-3 - PubMed
    1. Nature. 1976 Oct 28;263(5580):744-8 - PubMed
    1. Anal Biochem. 1976 Jul;74(1):73-93 - PubMed

Publication types

LinkOut - more resources