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Review
. 2017 Jun;64(3):729-745.
doi: 10.1111/tbed.12444. Epub 2015 Nov 13.

Review: Capripoxvirus Diseases: Current Status and Opportunities for Control

E S M Tuppurainen  1 , E H Venter  2 , J L Shisler  3 , G Gari  4 , G A Mekonnen  4 , N Juleff  5 , N A Lyons  6   7 , K De Clercq  8 , C Upton  9 , T R Bowden  10 , S Babiuk  11 , L A Babiuk  12
Affiliations
Review

Review: Capripoxvirus Diseases: Current Status and Opportunities for Control

E S M Tuppurainen et al. Transbound Emerg Dis. 2017 Jun.

Abstract

Lumpy skin disease, sheeppox and goatpox are high-impact diseases of domestic ruminants with a devastating effect on cattle, sheep and goat farming industries in endemic regions. In this article, we review the current geographical distribution, economic impact of an outbreak, epidemiology, transmission and immunity of capripoxvirus. The special focus of the article is to scrutinize the use of currently available vaccines to investigate the resource needs and challenges that will have to be overcome to improve disease control and eradication, and progress on the development of safer and more effective vaccines. In addition, field evaluation of the efficacy of the vaccines and the genomic database available for poxviruses are discussed.

Keywords: control; goatpox; immunity; lumpy skin disease; sheeppox; vaccines.

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Figures

Figure 1
Figure 1
Geographical distribution of lumpy skin disease. [Colour figure can be viewed at wileyonlinelibrary.com]
Figure 2
Figure 2
Geographical distribution of sheeppox and goatpox. [Colour figure can be viewed at wileyonlinelibrary.com]
See this image and copyright information in PMC

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