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. 2015 Nov 17;12(11):e1001901.
doi: 10.1371/journal.pmed.1001901. eCollection 2015 Nov.

The First Use of the Global Oral Cholera Vaccine Emergency Stockpile: Lessons from South Sudan

Abdinasir Abubakar  1 , Andrew S Azman  2 , John Rumunu  3 , Iza Ciglenecki  4 , Trina Helderman  5 , Haley West  6 , Justin Lessler  2 , David A Sack  2 , Stephen Martin  7 , William Perea  7 , Dominique Legros  7 , Francisco J Luquero  2   8
Affiliations

The First Use of the Global Oral Cholera Vaccine Emergency Stockpile: Lessons from South Sudan

Abdinasir Abubakar et al. PLoS Med. .

Abstract

Andrew Azman and colleagues describe their experience of deploying >250,000 doses of oral cholera vaccine in South Sudan in 2014

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Timeline of key vaccination events in South Sudan in 2014.
The dots on the timeline represent key vaccination-related events throughout the country. Labels are shown for a selection of events, with the complete timeline shown in S1 Fig. Colors represent different phases of the vaccination campaigns, with red representing planning events, yellow representing logistical activities leading up to the vaccine deployment, and green representing vaccination deployment activities. The epidemic curve is shown as grey vertical bars above.
Fig 2
Fig 2. Epidemic curves of suspected cholera cases in key vaccinated (green) and unvaccinated areas (blue).
Panels show the daily incidence rate of suspected cholera cases in the Juba community (A), the Juba PoC camps (B–C), Wau Shilluk camp (D), and Malakal PoC camp (E). Note that panels A–C have a break in the y-axis, as they had a much smaller incidence rate.
Fig 3
Fig 3. Illustration of the county-level attack rates in the 2014 cholera epidemic with respect to the vaccination locations (orange dots).
Grey areas represent counties with no suspected cholera cases.
See this image and copyright information in PMC

References

    1. United States Agency for International Development. Southern Sudan Health System Assessment. In: healthsystemassessment.com [Internet]. Jul 2007 [cited 27 Apr 2015]. http://www.healthsystemassessment.com/wp-content/uploads/2012/06/Sudan_G...
    1. WHO/UNICEF. Joint Monitoring Programme for Water Supply and Sanitation Progress on Sanitation and Drinking-Water: 2014 Update; World Health Organization: Geneva, Switzerland, 2014.
    1. Porta MI, Lenglet A, de Weerdt S, et al. Feasibility of a preventive mass vaccination campaign with two doses of oral cholera vaccine during a humanitarian emergency in South Sudan. Transactions of the Royal Society of Tropical Medicine and Hygiene 108(12):815 10.1093/trstmh/tru153 - DOI - PubMed
    1. Yen C, Hyde TB, Costa AJ, et al. The development of global vaccine stockpiles. The Lancet Infectious Diseases 2015;15(3):340–7. 10.1016/S1473-3099(14)70999-5 - DOI - PMC - PubMed
    1. Ciglenecki I, Sakoba K, Luquero FJ, Heile M, Itama C, Mengel M, et al. Feasibility of Mass Vaccination Campaign with Oral Cholera Vaccines in Response to an Outbreak in Guinea. PLoS Med 2013. September;10(9):e1001512 10.1371/journal.pmed.1001512 - DOI - PMC - PubMed

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