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Review
. 2015 Nov 15;142(22):3805-9.
doi: 10.1242/dev.129304.

Glia in mammalian development and disease

J Bradley Zuchero  1 , Ben A Barres  2
Affiliations
Review

Glia in mammalian development and disease

J Bradley Zuchero et al. Development. .

Abstract

Glia account for more than half of the cells in the mammalian nervous system, and the past few decades have witnessed a flood of studies that detail novel functions for glia in nervous system development, plasticity and disease. Here, and in the accompanying poster, we review the origins of glia and discuss their diverse roles during development, in the adult nervous system and in the context of disease.

Keywords: Astrocyte; Glia; Microglia; Myelination; Nervous system; Oligodendrocyte.

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Conflict of interest statement

Competing interests

The authors declare no competing or financial interests.

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