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Randomized Controlled Trial
. 2015 Nov;8(6):1044-51.
doi: 10.1161/CIRCHEARTFAILURE.115.002327.

Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients: Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)

Lauren B Cooper  1 , Robert J Mentz  2 , Jie-Lena Sun  2 , Phillip J Schulte  2 , Jerome L Fleg  2 , Lawton S Cooper  2 , Ileana L Piña  2 , Eric S Leifer  2 , William E Kraus  2 , David J Whellan  2 , Steven J Keteyian  2 , Christopher M O'Connor  2
Affiliations
Randomized Controlled Trial

Psychosocial Factors, Exercise Adherence, and Outcomes in Heart Failure Patients: Insights From Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION)

Lauren B Cooper et al. Circ Heart Fail. 2015 Nov.

Erratum in

  • Correction.
    [No authors listed] [No authors listed] Circ Heart Fail. 2016 Mar;9(3):e000014. doi: 10.1161/HHF.0000000000000014. Circ Heart Fail. 2016. PMID: 26920217 No abstract available.

Abstract

Background: Psychosocial factors may influence adherence with exercise training for heart failure (HF) patients. We aimed to describe the association between social support and barriers to participation with exercise adherence and clinical outcomes.

Methods and results: Of patients enrolled in Heart Failure: A Controlled Trial Investigating Outcomes of Exercise Training (HF-ACTION), 2279 (97.8%) completed surveys to assess social support and barriers to exercise, resulting in the perceived social support score (PSSS) and barriers to exercise score (BTES). Higher PSSS indicated higher levels of social support, whereas higher BTES indicated more barriers to exercise. Exercise time at 3 and 12 months correlated with PSSS (r= 0.09 and r= 0.13, respectively) and BTES (r=-0.11 and r=-0.12, respectively), with higher exercise time associated with higher PSSS and lower BTES (All P<0.005). For cardiovascular death or HF hospitalization, there was a significant interaction between the randomization group and BTES (P=0.035), which corresponded to a borderline association between increasing BTES and cardiovascular death or HF hospitalization in the exercise group (hazard ratio 1.25, 95% confidence interval 0.99, 1.59), but no association in the usual care group (hazard ratio 0.83, 95% confidence interval 0.66, 1.06).

Conclusions: Poor social support and high barriers to exercise were associated with lower exercise time. PSSS did not impact the effect of exercise training on outcomes. However, for cardiovascular death or HF hospitalization, exercise training had a greater impact on patients with lower BTES. Given that exercise training improves outcomes in HF patients, assessment of perceived barriers may facilitate individualized approaches to implement exercise training therapy in clinical practice.

Clinical trial registration: URL: http://www.clinicaltrials.gov. Unique identifier: NCT00047437.

Keywords: exercise; exercise therapy; heart failure; patients; social support.

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Figures

Figure 1
Figure 1
Study Patient Population
Figure 2
Figure 2
Relationship Between Baseline Perceived Social Support Scores and Barriers to Exercise Scores and Exercise Adherence. Panel A shows the minutes per week of exercise at 3 months by baseline PSSS, N=1073. Panel B shows the minutes per week of exercise at 12 months by baseline PSSS, N=909. Panel C shows the minutes per week of exercise at 3 months by baseline BTES, N=1073. Panel D shows the minutes per week of exercise at 12 months by baseline BTES, N=909.
Figure 3
Figure 3
Distribution of Perceived Social Support and Barriers to Exercise Scores at Baseline and 12 Months Panel A shows the distribution of PSSS at baseline. Panel B shows the distribution PSSS at 12 months. Panel C shows the distribution of BTES at baseline. Panel D shows the distribution of BTES at 12 months.
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