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Review
. 2015 Nov:90-91:49-73.
doi: 10.1016/j.pnmrs.2015.07.001. Epub 2015 Jul 11.

Applications of high dimensionality experiments to biomolecular NMR

Michał Nowakowski  1 , Saurabh Saxena  1 , Jan Stanek  1 , Szymon Żerko  1 , Wiktor Koźmiński  2
Affiliations
Review

Applications of high dimensionality experiments to biomolecular NMR

Michał Nowakowski et al. Prog Nucl Magn Reson Spectrosc. 2015 Nov.

Abstract

High dimensionality NMR experiments facilitate resonance assignment and precise determination of spectral parameters such as coupling constants. Sparse non-uniform sampling enables acquisition of experiments of high dimensionality with high resolution in acceptable time. In this review we present and compare some significant applications of NMR experiments of dimensionality higher than three in the field of biomolecular studies in solution.

Keywords: NMR spectroscopy; Non-uniform sampling; Proteins; RNA; Sparse sampling.

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