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Review
. 2015 Dec;36(4):657-68.
doi: 10.1016/j.ccm.2015.08.008. Epub 2015 Sep 11.

Cardiac Sarcoidosis

David Birnie  1 , Andrew C T Ha  2 , Lorne J Gula  3 , Santabhanu Chakrabarti  4 , Rob S B Beanlands  5 , Pablo Nery  5
Affiliations
Review

Cardiac Sarcoidosis

David Birnie et al. Clin Chest Med. 2015 Dec.

Abstract

Studies suggest clinically manifest cardiac involvement occurs in 5% of patients with pulmonary/systemic sarcoidosis. The principal manifestations of cardiac sarcoidosis (CS) are conduction abnormalities, ventricular arrhythmias, and heart failure. Data indicate that an 20% to 25% of patients with pulmonary/systemic sarcoidosis have asymptomatic (clinically silent) cardiac involvement. An international guideline for the diagnosis and management of CS recommends that patients be screened for cardiac involvement. Most studies suggest a benign prognosis for patients with clinically silent CS. Immunosuppression therapy is advocated for clinically manifest CS. Device therapy, with implantable cardioverter defibrillators, is recommended for some patients.

Keywords: Atrioventricular block; Cardiac sarcoidosis; Clinically manifest; Clinically silent; Heart failure; Sudden cardiac death; Ventricular arrhythmias.

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