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. 2015 Oct 1;6(10):4103-4112.
doi: 10.13040/IJPSR.0975-8232.6(10).4103-12.

Medicinal Plants: Their Use in Anticancer Treatment

M Greenwell, P K S M Rahman

Medicinal Plants: Their Use in Anticancer Treatment

M Greenwell et al. Int J Pharm Sci Res. .

Abstract

Globally cancer is a disease which severely effects the human population. There is a constant demand for new therapies to treat and prevent this life-threatening disease. Scientific and research interest is drawing its attention towards naturally-derived compounds as they are considered to have less toxic side effects compared to current treatments such as chemotherapy. The Plant Kingdom produces naturally occurring secondary metabolites which are being investigated for their anticancer activities leading to the development of new clinical drugs. With the success of these compounds that have been developed into staple drugs for cancer treatment new technologies are emerging to develop the area further. New technologies include nanoparticles for nano-medicines which aim to enhance anticancer activities of plant-derived drugs by controlling the release of the compound and investigating new methods for administration. This review discusses the demand for naturally-derived compounds from medicinal plants and their properties which make them targets for potential anticancer treatments.

Keywords: anticancer; cytotoxicity; epigenetics; polyphenols; secondary metabolites.

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References

    1. Ochwang’I DO, Kimwele CN, Oduma JA, Gathumbi PK, Mbaria JM, Kiama SG. Medicinal plants used in treatment and management of cancer in Kakamega County Kenya. Journal of Ethnopharmacology. 2014;151:1040–1055. - PubMed
    1. Cancer Research UK [Accessed 23 January 2015];What is cancer? 2014 Available at: http://www.cancerresearchuk.org/about-cancer/what-is-cancer.
    1. Sivaraj R, Rahman PKSM, Rajiv P, Vanathi P, Venckatesh R. Biosynthesis and characterization of Acalypha indica mediated copper oxide nanoparticles and evaluation of its antimicrobial and anticancer activity. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 2014;129:255–258. - PubMed
    1. Freiburghaus F, Kaminsky R, Nkunya MHH, Brun R. Evaluation of African plants for their in vitro trypanocidal activity. Journal of Ethnopharmacology. 1996;55:1–11. - PubMed
    1. Costa-Lotufo LV, Khan MTH, Ather A, Wilke DV, Jimenez PC, Pessoa C, Amaral de Moraes ME, Odorico de Moraes M. Studies of the anticancer potential of plants used in Bangladeshi folk medicine. Journal of Ethnopharmacology. 2005;99:21–30. - PubMed

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