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. 1989 Jun 15;339(6225):519-22.
doi: 10.1038/339519a0.

RNA-catalysed synthesis of complementary-strand RNA

J A Doudna  1 , J W Szostak
Affiliations

RNA-catalysed synthesis of complementary-strand RNA

J A Doudna et al. Nature. .

Abstract

The Tetrahymena ribozyme can splice together multiple oligonucleotides aligned on a template strand to yield a fully complementary product strand. This reaction demonstrates the feasibility of RNA-catalysed RNA replications.

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