Radiotherapy of Ductal Carcinoma In Situ
- PMID: 26600762
- PMCID: PMC4608608
- DOI: 10.1159/000437452
Radiotherapy of Ductal Carcinoma In Situ
Abstract
Ductal carcinoma in situ (DCIS) is a heterogeneous disease in both its biology and clinical course. In the past, recurrence rates after breast-conserving surgery have been as high as 30% after 10 years. The introduction of mammography screening and advances in imaging have led to an increase in the detection of DCIS. The focus of this review is on the role of radiotherapy in the multidisciplinary treatment, including current developments in hypofractionation and boost delivery, and attempts to define low-risk subsets of DCIS for which the need for adjuvant radiation is repeatedly questioned.
Keywords: Boost; Ductal carcinoma in situ (DCIS); Hypofractionation; Low-risk subgroup; Radiotherapy.
References
-
- Souchon R, Sautter-Bihl ML, Sedlmayer F, et al. DEGRO practical guidelines: Radiotherapy of breast cancer II: Radiotherapy of non-invasive neoplasia of the breast. Strahlenther Onkol. 2014;190:8–16. - PubMed
-
- Warnberg F, Garmo H, Emdin S, et al. Effect of radiotherapy after breast-conserving surgery for ductal carcinoma in situ: 20 years follow-up in the randomized SweDCIS trial. J Clin Oncol. 2014;32:3613–3618. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous
