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Review
. 2016 Mar-Apr;40(2):330-8.
doi: 10.1016/j.clinimag.2015.09.016. Epub 2015 Sep 21.

Application of quantitative computed tomography for assessment of trabecular bone mineral density, microarchitecture and mechanical property

Song Shou Mao  1 , Dong Li  2 , Yanting Luo  3 , Younus Saleem Syed  4 , Matthew J Budoff  5
Affiliations
Free article
Review

Application of quantitative computed tomography for assessment of trabecular bone mineral density, microarchitecture and mechanical property

Song Shou Mao et al. Clin Imaging. 2016 Mar-Apr.
Free article

Abstract

Osteoporosis is a common metabolic bone disease, causing increased skeletal fragility characterized by a low bone mass and trabecular microarchitectural deterioration. Assessment of the bone mineral density (BMD) is the primary determinant of skeletal fragility. Computed tomography (CT)-based trabecular microarchitectural and mechanical assessments are important methods to evaluate the skeletal strength. In this review, we focus the feasibility of QCT BMD measurement using a calibration phantom or phantomless. The application of QCT could extend the bone mineral density assessment to all patients who underwent a heart, lung, whole-body, and as well as all routine clinical implications of CT scan.

Keywords: Bone mineral density; Calibration phantom; Multi-row detector CT; Quantitative CT.

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