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Case Reports
. 2016 Feb;14(1):e115-8.
doi: 10.1016/j.clgc.2015.09.011. Epub 2015 Sep 30.

PSMA-Based Detection of Prostate Cancer Bone Lesions With ¹⁸F-DCFPyL PET/CT: A Sensitive Alternative to (⁹⁹m)Tc-MDP Bone Scan and Na¹⁸F PET/CT?

Steven P Rowe  1 , Margarita Mana-Ay  2 , Mehrbod S Javadi  1 , Zsolt Szabo  1 , Jeffrey P Leal  3 , Martin G Pomper  1 , Kenneth J Pienta  4 , Ashley E Ross  2 , Michael A Gorin  5
Affiliations
Case Reports

PSMA-Based Detection of Prostate Cancer Bone Lesions With ¹⁸F-DCFPyL PET/CT: A Sensitive Alternative to (⁹⁹m)Tc-MDP Bone Scan and Na¹⁸F PET/CT?

Steven P Rowe et al. Clin Genitourin Cancer. 2016 Feb.
No abstract available

Keywords: Bone metastases; DCFPyL; PET/CT; PSMA; Prostate cancer.

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Figures

Figure 1
Figure 1
(A) Anterior projection whole body planar 99mTc-MDP bone scan, (B) anterior view of the MIP from the Na18F PET, (C) anterior view of the MIP from the 18F-DCFPyL PET, and (D) anterior view of the MIP from the 18F-DCFPyL PET with sites of abnormal radiotracer uptake within lymph nodes masked with a red overlay. Note the increasing number of visible lesions with Na18F PET relative to 99mTc-MDP bone scan and with 18F-DCFPyL PET relative to either of the other two modalities.
Figure 2
Figure 2
(A) Axial fused 18F-DCFPyL PET/CT and (B) axial fused Na18F PET/CT images through the proximal thighs demonstrating a lesion with intense 18F-DCFPyL uptake in the marrow space of the left femur that is occult with Na18F (red arrowheads).
Figure 3
Figure 3
(A) Axial fused 18F-DCFPyL PET/CT and (B) axial fused Na18F PET/CT images through the C5 level of the cervical spine with a lesion in the right lateral mass that is clearly visible with 18F-DCFPyL but demonstrates no uptake on the Na18F scan (red arrowheads).
See this image and copyright information in PMC

References

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