Can Helminth Infection Reverse Microbial Dysbiosis?
- PMID: 26604162
- PMCID: PMC4752385
- DOI: 10.1016/j.pt.2015.10.001
Can Helminth Infection Reverse Microbial Dysbiosis?
Abstract
There is growing interest in treating inflammatory conditions with helminth infection. Recently, Loukas and colleagues have reported promising results from using experimental hookworm infection to reduce gluten sensitivity in celiac disease patients. Analysis of microbiota samples from the trial is contributing to our understanding of the complexity underlying helminth–microbiota–host relationships.
Comment on
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Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects.Sci Rep. 2015 Sep 18;5:13797. doi: 10.1038/srep13797. Sci Rep. 2015. PMID: 26381211 Free PMC article.
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References
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- Croese J, et al. Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease. J Allergy Clin Immunol. 2015;135:508–516e505. - PubMed
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