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Comment
. 2015 Nov;31(11):534-535.
doi: 10.1016/j.pt.2015.10.001.

Can Helminth Infection Reverse Microbial Dysbiosis?

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Comment

Can Helminth Infection Reverse Microbial Dysbiosis?

P'ng Loke et al. Trends Parasitol. 2015 Nov.

Abstract

There is growing interest in treating inflammatory conditions with helminth infection. Recently, Loukas and colleagues have reported promising results from using experimental hookworm infection to reduce gluten sensitivity in celiac disease patients. Analysis of microbiota samples from the trial is contributing to our understanding of the complexity underlying helminth–microbiota–host relationships.

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References

    1. Weinstock JV. Autoimmunity: The worm returns. Nature. 2012;491:183–185. - PMC - PubMed
    1. Feary JR, et al. Experimental hookworm infection: a randomized placebo-controlled trial in asthma. Clin Exp Allergy. 2010;40:299–306. - PMC - PubMed
    1. Daveson AJ, et al. Effect of hookworm infection on wheat challenge in celiac disease-a randomised double-blinded placebo controlled trial. PLoS One. 2011;6:e17366. - PMC - PubMed
    1. Croese J, et al. Experimental hookworm infection and gluten microchallenge promote tolerance in celiac disease. J Allergy Clin Immunol. 2015;135:508–516e505. - PubMed
    1. Giacomin P, et al. Experimental hookworm infection and escalating gluten challenges are associated with increased microbial richness in celiac subjects. Sci Rep. 2015;5:13797. - PMC - PubMed

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