Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Dec;5(1):36.
doi: 10.1186/s12348-015-0067-7. Epub 2015 Nov 25.

Traumatic endophthalmitis caused by Nocardia kruczakiae in a patient with traumatic eye injury

Rafael Barraquer Compte  1   2 , Hernán Martínez-Osorio  3   4 , Gema Carrasco  5 , Betty Lorente  6   7 , Javier Elizalde  8   9 , Sylvia Valdezate  10 , Ramón Lorente  11 , Emilio Iglesias  12 , Juan Antonio Saez-Nieto  13
Affiliations

Traumatic endophthalmitis caused by Nocardia kruczakiae in a patient with traumatic eye injury

Rafael Barraquer Compte et al. J Ophthalmic Inflamm Infect. 2015 Dec.

Abstract

Background: We describe a case of traumatic ocular endophthalmitis caused by Nocardia kruczakiae after vegetable trauma in an immunocompetent child.

Findings: A 5-year-old boy suffered from a trauma with a palm tree leaflet. Two months later, he was diagnosed with traumatic infectious uveitis and intumescent cataract with anterior capsule rupture. Intensive treatment with systemic and topical vancomycin, ceftazidime and methylprednisolone began. After 1 month, he underwent phacoemulsification with intraocular lens implantation (IOL). After some episodes of reactivation, he was diagnosed with traumatic nocardial endophthalmitis from aqueous humour samples. Several operations and specific antibiotic therapy resolved the infection.

Conclusions: In cases of traumatic endophthalmitis and several recurrences, it is extremely useful to make an etiologic diagnosis in order to treat the patient with specific antibiotics.

Keywords: Bacterial endophthalmitis; Multi-targeted identification; Nocardia kruczakiae.

PubMed Disclaimer

Figures

Fig. 1
Fig. 1
Left eye N. krckzakiae endophthalmitis. The slit lamp examination shows yellowish nodules in anterior chamber above iris and intraocular lens
See this image and copyright information in PMC

References

    1. Clinical and Laboratory Standards Institute/National Committee for Clinical Laboratory Standards (2011). Susceptibility testing of Mycobacteria, Nocardiae, and other aerobic actinomycetes;. In: Wayne, PA. National Committee for Clinical Laboratory Standards, Approved standard 2nd edn. CLSI document M24-A2. - PubMed
    1. Conville PS, Brown JM, Steigerwalt AG, Lee JW, Anderson VL, Fishbain JT, Holland SM, Witebsky FG. Nocardia kruczakiae sp. nov., a pathogen in immunocompromised patients and a member of the “N. nova complex”. J Clin Microbiol. 2004;42:5139–5145. doi: 10.1128/JCM.42.11.5139-5145.2004. - DOI - PMC - PubMed
    1. Takeda K, Kang Y, Yazawa K, Gonoi T, Mikami Y. Phylogenetic studies of Nocardia species based on gyrB gene analyses. J Med Microbial. 2010;59:165–171. doi: 10.1099/jmm.0.011346-0. - DOI - PubMed
    1. Oh WS, Ko KS, Song JH, Lee MY, Ryu SY, Taek S, Heo ST, Kwon KT, Lee JH, Peck KR, Lee NY. Catheter-associated bacteremia by Mycobacterium senegalense in Korea. BMC Infect Dis. 2005;5:107. doi: 10.1186/1471-2334-5-107. - DOI - PMC - PubMed
    1. McTaggart LR, Richardson SE, Witkowska M, Zhang SX. Phylogeny and identification of Nocardia species on the basis of multilocus sequence analysis. J Clin Microbiol. 2010;48:4525–4533. doi: 10.1128/JCM.00883-10. - DOI - PMC - PubMed

LinkOut - more resources