Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Dec;52(12):7577-87.
doi: 10.1007/s13197-015-1921-1. Epub 2015 Jul 22.

Probiotics, prebiotics and synbiotics- a review

Affiliations
Review

Probiotics, prebiotics and synbiotics- a review

Kavita R Pandey et al. J Food Sci Technol. 2015 Dec.

Abstract

The health benefits imparted by probiotics and prebiotics as well as synbiotics have been the subject of extensive research in the past few decades. These food supplements termed as functional foods have been demonstrated to alter, modify and reinstate the pre-existing intestinal flora. They also facilitate smooth functions of the intestinal environment. Most commonly used probiotic strains are: Bifidobacterium, Lactobacilli, S. boulardii, B. coagulans. Prebiotics like FOS, GOS, XOS, Inulin; fructans are the most commonly used fibers which when used together with probiotics are termed synbiotics and are able to improve the viability of the probiotics. Present review focuses on composition and roles of Probiotics, Prebiotics and Synbiotics in human health. Furthermore, additional health benefits like immune-modulation, cancer prevention, inflammatory bowel disease etc. are also discussed. Graphical abstractPictorial summary of health benefits imparted by probiotics, prebiotics and synbiotics.

Keywords: Cancer; Cardiovascular diseases; Intestinal disorders; Prebiotics; Probiotics; Synbiotics.

PubMed Disclaimer

Figures

Graphical abstract
Graphical abstract
Pictorial summary of health benefits imparted by probiotics, prebiotics and synbiotics
Fig. 1
Fig. 1
Characteristics of an ideal probiotic strain

References

    1. Abrams SA, Griffin IJ, Hawthorne KM, Liang L, Gunn SK, Darlington G, Ellis KJ. A combination of prebiotic short-and long-chain inulin-type fructans enhances calcium absorption and bone mineralization in young adolescents. Am J Clin Nutr. 2005;82(2):471–476. - PubMed
    1. Andrews JM, Tan M. Probiotics in luminal gastroenterology: the current state of play. Intern Med J. 2012;42(12):1287–1291. doi: 10.1111/imj.12015. - DOI - PubMed
    1. Artiss JD, Brogan K, Brucal M, Moghaddam M, Jen KLC. The effects of a new soluble dietary fiber on weight gain and selected blood parameters in rats. Metabolism. 2006;55(2):195–202. doi: 10.1016/j.metabol.2005.08.012. - DOI - PubMed
    1. Bartlett JG. Antibiotic-associated diarrhea. N Engl J Med. 2002;346(5):334–339. doi: 10.1056/NEJMcp011603. - DOI - PubMed
    1. Bonnema AL, Kolberg LW, Thomas W, Slavin JL. Gastrointestinal tolerance of chicory inulin products. J Am Diet Assoc. 2010;110(6):865–868. doi: 10.1016/j.jada.2010.03.025. - DOI - PubMed