Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015 Oct-Dec;31(4):273-82.
doi: 10.4103/0970-1591.166448.

Biomarkers for non-muscle invasive bladder cancer: Current tests and future promise

Fadi Darwiche  1 , Dipen J Parekh  1 , Mark L Gonzalgo  1
Affiliations
Review

Biomarkers for non-muscle invasive bladder cancer: Current tests and future promise

Fadi Darwiche et al. Indian J Urol. 2015 Oct-Dec.

Abstract

The search continues for optimal markers that can be utilized to improve bladder cancer detection and to predict disease recurrence. Although no single marker has yet replaced the need to perform cystoscopy and urine cytology, many tests have been evaluated and are being developed. In the future, these promising markers may be incorporated into standard practice to address the challenge of screening in addition to long-term surveillance of patients who have or are at risk for developing bladder cancer.

Keywords: Biomarkers; bladder cancer; transitional cell carcinoma; urothelial carcinoma.

PubMed Disclaimer

References

    1. Burger M, Catto JW, Dalbagni G, Grossman HB, Herr H, Karakiewicz P, et al. Epidemiology and risk factors of urothelial bladder cancer. Eur Urol. 2013;63:234–41. - PubMed
    1. Mossanen M, Gore JL. The burden of bladder cancer care: Direct and indirect costs. Curr Opin Urol. 2014;24:487–91. - PubMed
    1. Giannopoulos A, Manousakas T, Mitropoulos D, Botsoli-Stergiou E, Constantinides C, Giannopoulou M, et al. Comparative evaluation of the BTAstat test, NMP22, and voided urine cytology in the detection of primary and recurrent bladder tumors. Urology. 2000;55:871–5. - PubMed
    1. Grégoire M, Fradet Y, Meyer F, Têtu B, Bois R, Bédard G, et al. Diagnostic accuracy of urinary cytology, and deoxyribonucleic acid flow cytometry and cytology on bladder washings during follow-up for bladder cancer. J Urol. 1997;157:1660–4. - PubMed
    1. Grossman HB. New methods for detection of bladder cancer. Semin Urol Oncol. 1998;16:17–22. - PubMed