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Review
. 2015 May-Aug;19(2):230-8.
doi: 10.4103/0973-029X.164537.

β catenin in health: A review

Affiliations
Review

β catenin in health: A review

Sharada Prakash et al. J Oral Maxillofac Pathol. 2015 May-Aug.

Abstract

β catenin belongs to the armadillo family of proteins. It plays a crucial role in developmental and homeostatic processes. Wnts are a family of 19 secreted glycoproteins that transduce multiple signaling cascades, including the canonical Wnt/β catenin pathway, Wnt/Ca(2+) pathway and the Wnt/polarity pathway. This is a review on β catenin, Wnt proteins and their secretion, the signaling pathway, the associated factors and the crucial role of β catenin in odontogenesis.

Keywords: Odontogenesis; Wnt proteins; Wnt signaling; β catenin.

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References

    1. Valenta T, Hausmann G, Basler K. The many faces and functions of β-catenin. EMBO J. 2012;31:2714–36. - PMC - PubMed
    1. Daugherty RL, Gottardi CJ. Phospho-regulation of Beta-catenin adhesion and signaling functions. Physiology (Bethesda) 2007;22:303–9. - PMC - PubMed
    1. Voronkov A, Krauss S. Wnt/beta-catenin signaling and small molecule inhibitors. Curr Pharm Des. 2013;19:634–64. - PMC - PubMed
    1. Zhao ZM, Reynolds AB, Gaucher EA. The evolutionary history of the catenin gene family during metazoan evolution. BMC Evol Biol. 2011;11:198. - PMC - PubMed
    1. Xu W, Kimelman D. Mechanistic insights from structural studies of beta-catenin and its binding partners. J Cell Sci. 2007;120(Pt 19):3337–44. - PubMed