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Review
. 1989 Mar-Apr;48(2):57-62.

[Neonatal lupus erythematosus]

[Article in German]
W J Mayet  1 , E Hermann, M Bachmann, T Poralla, K H Meyer zum Büschenfelde
Affiliations
  • PMID: 2660470
Review

[Neonatal lupus erythematosus]

[Article in German]
W J Mayet et al. Z Rheumatol. 1989 Mar-Apr.

Abstract

The neonatal lupus erythematosus syndrome, first described by McCuistion and Schoch in 1954, is associated with characteristic skin lesions and congenital heart block in the new-born, and the presence of Ro-(SSA), La-(SSB), or RNP antibodies in mothers and infants. A transplacental transference of maternal autoantibodies is discussed as possible pathophysiologic mechanism in neonatal lupus. The symptoms, the onset, and recently published pathogenetic concepts are reviewed.

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