The marker C-reactive protein is helpful in monitoring the integrity of anastomosis: plasma calprotectin

Abstract

Background: Despite improved surgical techniques and materials, anastomotic leakage is a big problem for surgeons. The most frequently used laboratory parameters is leukocyte (white blood cell) and C-reactive protein (CRP). Availability of plasma calprotectin with CRP to detect anastomotic leakage was studied.

Methods: In this prospective study of 41 (male/female 18/23) patients in the anastomosis group, 30 (male/female 20/10) patients were included in the control group. The anastomosis groups viewed in preoperatively day and postoperatively 1st, 3rd, and 5th day of CRP, white blood cell, and plasma calprotectin values.

Results: Anastomosis group with complications and without complications were studied. Statistically significant similarities between plasma calprotectin and CRP levels in the postoperative period were observed.

Conclusion: Plasma calprotectin in monitoring the integrity of the anastomosis can be used with a marker CRP.

Keywords: Anastomoses; C-reactive protein; Leakage; Plasma calprotectin.