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Case Reports
. 2016 Apr;16(2):136-8.
doi: 10.1136/practneurol-2015-001166. Epub 2015 Nov 25.

Capnocytophaga canimorsus meningitis diagnosed by 16S rRNA PCR

T M J Beernink  1 , P C Wever  2 , M H A Hermans  3 , M G T Bartholomeus  1
Affiliations
Case Reports

Capnocytophaga canimorsus meningitis diagnosed by 16S rRNA PCR

T M J Beernink et al. Pract Neurol. 2016 Apr.

Abstract

Capnocytophaga canimorsus is a common Gram-negative anaerobic bacterium from the oral flora of dogs, typically transmitted to humans by dog bites. We report a case of C. canimorsus meningitis where there was (on presentation) no apparent predisposing risk factor and in whom we used 16S rRNA PCR gene sequencing to identify the pathogen quickly and to switch to appropriate antibiotic therapy. Physicians should be aware of potential C. canimorsus meningitis if conventional cerebrospinal fluid bacterial culture is negative but Gram staining identifies bacteria, especially in patients with a recent dog bite or known immunodeficiency.

Keywords: BACTERIOLOGY; CLINICAL NEUROLOGY; INFECTIOUS DISEASES; MICROBIOLOGY.

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