Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Nov;40(11):747-73.

Parkinson's Disease and Its Management: Part 4: Treatment of Motor Complications

George DeMaagd, Ashok Philip

Parkinson's Disease and Its Management: Part 4: Treatment of Motor Complications

George DeMaagd et al. P T. 2015 Nov.

Abstract

Parkinson's motor complications include wearing-off, a delayed or absent response to carbidopa/levodopa therapy, freezing of gait, dyskinesias, and dystonias. Treatment may include medication adjustments, such as increased dopaminergic stimulation.

PubMed Disclaimer

References

    1. Stocchi F, Jenner P, Obeso JA. When do levodopa motor fluctuations first appear in Parkinson’s disease? Eur Neurol. 2010;63:257–266. - PubMed
    1. Gershanik OS. Clinical problems in late-stage Parkinson’s disease. J Neurol. 2010;257(suppl 2):S288–S291. - PubMed
    1. Pahwa R, Factor SA, Lyons KE, et al. Practice parameter: treatment of Parkinson disease with motor fluctuations and dyskinesia (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2006;66:983–995. - PubMed
    1. Olanow CW, Kieburtz K, Rascol O, et al. Factors predictive of the development of levodopa-induced dyskinesia and wearing-off in Parkinson’s disease. Mov Disord. 2013;28:1064–1071. - PubMed
    1. Kim HS, Cheon SM, Seo JW, et al. Nonmotor symptoms more closely related to Parkinson’s disease: comparison with normal elderly. J Neurol Sci. 2013;324:70–73. - PubMed

LinkOut - more resources