Not low hanging but still sweet: Metabolic proteomes in cardiovascular disease
- PMID: 26611885
- DOI: 10.1016/j.yjmcc.2015.11.022
Not low hanging but still sweet: Metabolic proteomes in cardiovascular disease
Abstract
The application of proteomics in biology and medicine has reached a moment of truth. The demand of biologists for transformative insights into how cells work, plus the mandate of basic science research to ultimately impact clinical medicine, crystallize as a test on the rigor and reproducibility of any 'omics measurement. Studies like that by Boylston et al. indicate that proteomics can pass that test.
Keywords: Heart disease; Heart failure; Ischemia; Metabolism; Mitochondria; Myocardial; Proteomics; Systems biology.
Copyright © 2015 Elsevier Ltd. All rights reserved.
Comment on
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Characterization of the cardiac succinylome and its role in ischemia-reperfusion injury.J Mol Cell Cardiol. 2015 Nov;88:73-81. doi: 10.1016/j.yjmcc.2015.09.005. Epub 2015 Sep 24. J Mol Cell Cardiol. 2015. PMID: 26388266 Free PMC article.
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