Hairy cell leukemia: Past, present and future
- PMID: 26614906
- PMCID: PMC5008915
- DOI: 10.1016/j.beha.2015.10.015
Hairy cell leukemia: Past, present and future
Abstract
This brief review highlights the sequence of therapeutic milestones and advances in our understanding of the biology of hairy cell leukemia (HCL) with a focus on recent molecular findings and how these may be applied to improve disease outcomes in the future. Targeted therapy is discussed in the context of the recently identified BRAF mutation and other genetic findings.
Keywords: BRAF; Hairy cell leukemia; Vemurafenib.
Copyright © 2015. Published by Elsevier Ltd.
Conflict of interest statement
None.
References
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- Quesada JR, et al. Alpha interferon for induction of remission in hairy-cell leukemia. N Engl J Med. 1984;310(1):15–8. - PubMed
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