Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2016 Jan;27(1):111-21.
doi: 10.1016/j.nec.2015.08.012.

Responsive Direct Brain Stimulation for Epilepsy

Martha J Morrell  1 , Casey Halpern  2
Affiliations
Review

Responsive Direct Brain Stimulation for Epilepsy

Martha J Morrell et al. Neurosurg Clin N Am. 2016 Jan.

Abstract

Closed-loop, responsive focal brain stimulation provides a new treatment option for patients with refractory partial onset seizures who are not good candidates for potentially curative epilepsy surgery. The first responsive brain neurostimulator (RNS® System, NeuroPace), provides stimulation directly to the seizure focus when abnormal electrocorticographic is detected. Seizure reductions of 44% at one year increase to 60 to 66% at years 3 to 6 of treatment. There is no negative impact on cognition and mood. Risks are similar to other implanted medical devices and therapeutic stimulation is not perceived.

Keywords: Closed-loop; Electrocorticogram; Epilepsy; Intracranial; Intractable; Neurostimulator; Responsive; Stimulation.

PubMed Disclaimer