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. 2016 Jan;92(1):78-81.
doi: 10.1016/j.jhin.2015.10.012. Epub 2015 Nov 9.

Risk factors for carbapenemase-producing Enterobacteriaceae colonization of asymptomatic carriers on admission to an Italian rehabilitation hospital

A Rossini  1 , S G Di Santo  2 , M F Libori  2 , V Tiracchia  2 , M P Balice  2 , A Salvia  2
Affiliations

Risk factors for carbapenemase-producing Enterobacteriaceae colonization of asymptomatic carriers on admission to an Italian rehabilitation hospital

A Rossini et al. J Hosp Infect. 2016 Jan.

Abstract

The spread of carbapenemase-producing Enterobacteriaceae (CPE) has become a worldwide problem. Early identification and isolation of asymptomatic carriers are important for infection prevention and control measures. All inpatients (N=1427) admitted to 'Fondazione Santa Lucia' Rehabilitation Hospital in 2014 were screened by rectal swab; 10.2% of them were CPE-colonized. The multivariate analysis on anamnestic data showed that both previous admission to an intensive care unit (odds ratio: 4.04; 95% confidence interval: 2.20-7.44; P<0.001) or post-acute care hospitals (2.88; 1.74-4.77; P<0.001) and presence of a central venous catheter (2.19; 1.34-3.59; P<0.001) were significant risk factors.

Keywords: Carbapenemase; Carriage; Rehabilitation; Resistance epidemiology; Surveillance.

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