Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015:2015:179483.
doi: 10.1155/2015/179483. Epub 2015 Nov 4.

Brainstem Tuberculoma in Pregnancy

Affiliations

Brainstem Tuberculoma in Pregnancy

Dana A Muin et al. Case Rep Obstet Gynecol. 2015.

Abstract

We report a case of a Somali refugee who presented in the second trimester of her first pregnancy with a four-week history of gradual right-sided sensomotoric hemisyndrome including facial palsy and left-sided paresis of the oculomotorius nerve causing drooping of the left eyelid and double vision. Cranial magnetic resonance imaging revealed a solitary brainstem lesion. Upon detection of hilar lymphadenopathy on chest X-ray (CXR), the diagnosis of disseminated tuberculosis with involvement of the central nervous system was confirmed by PCR and treatment induced with rifampicin, isoniazid, pyrazinamide, and ethambutol. The patient had a steady neurological improvement and a favorable pregnancy outcome.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Tuberculoma in the left pedunculus cerebri at time of first encounter (frontal view).
Figure 2
Figure 2
Tuberculoma in the left pedunculus cerebri at time of first encounter (horizontal view).
Figure 3
Figure 3
Fetal weight curve.
Figure 4
Figure 4
Chest X-ray.
Figure 5
Figure 5
Tuberculoma after 1 month (frontal view).
Figure 6
Figure 6
Tuberculoma after 1 month (horizontal view).
Figure 7
Figure 7
Tuberculoma after 2 months (frontal view).
Figure 8
Figure 8
Tuberculoma after 2 months (horizontal view).

References

    1. World Health Organization (WHO) 2015, http://www.who.int/mediacentre/factsheets/fs104/en/
    1. Sugarman J., Colvin C., Moran A. C., Oxlade O. Tuberculosis in pregnancy: an estimate of the global burden of disease. The Lancet Global Health. 2014;2(12):e710–e716. doi: 10.1016/s2214-109x(14)70330-4. - DOI - PubMed
    1. Ropper A. G. B. R. Infections of the Nervous System. 8th 2005.
    1. Hernandez Pando R., Aguilar D., Cohen I., et al. Specific bacterial genotypes of Mycobacterium tuberculosis cause extensive dissemination and brain infection in an experimental model. Tuberculosis. 2010;90(4):268–277. doi: 10.1016/j.tube.2010.05.002. - DOI - PubMed
    1. Fitzgerald D. H. D. Mycobacterium tuberculosis. 6th. Philadelphia, Pa, USA: Elsevier Churchill Livingstone; 2005. (edited by: G. L. B. J. Mandell, R. Dolin).

LinkOut - more resources