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. 2015 Aug;10(2):705-708.
doi: 10.3892/ol.2015.3357. Epub 2015 Jun 10.

Desmoplastic small-round-cell tumor of the abdomen: A report of two rare cases

Jiajia Chen  1 , Jifang Sheng  1 , Lijun Wang  2 , Zhao-Ming Wang  2 , Lanjuan Li  1
Affiliations

Desmoplastic small-round-cell tumor of the abdomen: A report of two rare cases

Jiajia Chen et al. Oncol Lett. 2015 Aug.

Abstract

Desmoplastic small-round-cell tumor (DSRCT) is an uncommon type of malignancy, which primarily occurs in adolescent males and develops in the abdominal cavity. The present study reports the case of two manifestations of DSRCT complicated with other diseases, which involved the invasion of the pelvis or abdominal vessels. The first case was of a 25-year-old man with repeated diarrhea and abdominal distension for 9 months; the second case was of a 68-year-old man who presented with persistent abdominal pain for 20 days. In each patient, a mass was identified in the abdomen and biopsies were performed in order to reach a diagnosis. Immunohistochemical staining of the biopsy material revealed a diagnosis of DSRCT in each case. In addition, the present study aimed to discuss the use of imaging techniques in providing evidence for the early diagnosis of DSRCT.

Keywords: education; gastrointestinal cancers; radiology.

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Figures

Figure 1.
Figure 1.
CT scans of the patient in Case 1. (A) A hypodense cystic-solid mixed mass was identified in the liver (arrow), with intrahepatic metastasis. (B) Multiple soft tissue mass lesions with internal calcification were located in the mesentery (arrow). (C) Ascites peritoneal thickening (white arrow) and right-sided hydronephrosis (arrow) were observed. (D) Contrast-enhanced CT image [of the same view as (A)] revealed a heterogeneously-enhanced mass lesion. (E) Contrast-enhanced CT image of the abdomen [same view as (B)] revealed a heterogeneously-enhanced mass lesion. (F) Contrast-enhanced CT scan of the pelvis identified a large soft tissue mass lesion (arrow) with invasion of the bladder and colon. CT, computed topography.
Figure 2.
Figure 2.
Immunohistochemical analysis of the biopsy specimen from the patient in Case 1. The results of the immunohistochemical analysis revealed that the membranous pattern of the biopsy specimen was positive for (A) CD99, (B) cytokeratin, (C) desmin and (D) vimentin (magnification, x400).
Figure 3.
Figure 3.
Case 2. Contrast-enhanced computed tomography image revealed low density in the inferior vena cava (arrow).
Figure 4.
Figure 4.
Case 2. Endoscopy revealed protruding lesions with erosion and ulceration on the gastric body.
See this image and copyright information in PMC

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