Dose-Finding Trials: Optimizing Phase 2 Data in the Drug Development Process

Affiliations

¹ Berry Consultants LLC, Austin, Texas.
² Berry Consultants LLC, Austin, Texas2University of Central Florida College of Medicine, Orlando.

Comment

Kert Viele et al. JAMA. 2015.

. 2015 Dec 1;314(21):2294-5.

doi: 10.1001/jama.2015.16702.

¹ Berry Consultants LLC, Austin, Texas.
² Berry Consultants LLC, Austin, Texas2University of Central Florida College of Medicine, Orlando.

No abstract available

Comment on

Effect of Vericiguat, a Soluble Guanylate Cyclase Stimulator, on Natriuretic Peptide Levels in Patients With Worsening Chronic Heart Failure and Reduced Ejection Fraction: The SOCRATES-REDUCED Randomized Trial.
Gheorghiade M, Greene SJ, Butler J, Filippatos G, Lam CS, Maggioni AP, Ponikowski P, Shah SJ, Solomon SD, Kraigher-Krainer E, Samano ET, Müller K, Roessig L, Pieske B; SOCRATES-REDUCED Investigators and Coordinators. Gheorghiade M, et al. JAMA. 2015 Dec 1;314(21):2251-62. doi: 10.1001/jama.2015.15734. JAMA. 2015. PMID: 26547357 Clinical Trial.