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Randomized Controlled Trial
. 2016 Jun;41(5):522-30.
doi: 10.1093/jpepsy/jsv114. Epub 2015 Nov 30.

Mediators of Treatment Effects in a Randomized Clinical Trial of Multisystemic Therapy-Health Care in Adolescents With Poorly Controlled Asthma: Disease Knowledge and Device Use Skills

Deborah A Ellis  1 , Pamela King  2 , Sylvie Naar-King  2
Affiliations
Randomized Controlled Trial

Mediators of Treatment Effects in a Randomized Clinical Trial of Multisystemic Therapy-Health Care in Adolescents With Poorly Controlled Asthma: Disease Knowledge and Device Use Skills

Deborah A Ellis et al. J Pediatr Psychol. 2016 Jun.

Abstract

Objective: Determine whether Multisystemic Therapy-Health Care (MST-HC) improved asthma knowledge and controller device use skills among African-American youth with poorly controlled asthma and whether any improvements mediated changes in illness management.

Methods: A randomized controlled trial was conducted with 170 adolescents with moderate to severe asthma. Families were randomized to MST-HC or attention control. Data were collected at baseline and 6 and 12 months after intervention completion.

Results: In linear mixed models, adolescents in the MST-HC group had increases in asthma knowledge; asthma knowledge was unchanged for attention control. Controller device use skills increased for adolescents in the MST-HC group, while skills declined for attention control. Both knowledge and skills mediated the relationship between intervention condition and changes in illness management.

Conclusions: Tailored, home-based interventions that include knowledge and skills building components are one means by which illness management in African-American youth with poorly controlled asthma can be improved.

Keywords: adherence; asthma; family therapy.

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Figures

Figure 1.
Figure 1.
Difference between MST-HC and FS groups in asthma knowledge from baseline to 6-month postintervention follow-up (treatment × time interaction, p < .05).
Figure 2.
Figure 2.
Difference between MST-HC and FS groups in controller device use skills from baseline to 6-month postintervention follow-up (treatment × time interaction p < .05).
See this image and copyright information in PMC

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