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Case Reports
. 2015 Dec 1:2015:bcr2015212735.
doi: 10.1136/bcr-2015-212735.

Live kidney donation from a person with haemophilia

Christopher McCauley  1 , Agnes Masengu  2 , Aisling E Courtney  2 , Gary Benson  3
Affiliations
Case Reports

Live kidney donation from a person with haemophilia

Christopher McCauley et al. BMJ Case Rep. .

Abstract

There are many documented cases of a person with haemophilia successfully receiving a solid organ transplant, including liver and kidney. However, there is no literature reporting live organ donation by a person with haemophilia. Presumably, this is because the associated risks of excessive bleeding, inhibitor development after a period of intensive treatment with factor replacement and the possibility of variant Creutzfeldt-Jakob disease transmission in those previously treated with blood products, are considered excessive. This case describes a 24-year-old man who was diagnosed with mild haemophilia A during his pretransplant work up as a potential live kidney donor to his sister. He then went on to successfully donate his kidney, without complications. To the best of our knowledge, this is the first description of a person with haemophilia being a living organ donor.

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References

    1. Gordon FH, Mistry PK, Sabin CA et al. . Outcome of orthotopic liver transplantation in patients with haemophilia. Gut 1998;42:744–9. 10.1136/gut.42.5.744 - DOI - PMC - PubMed
    1. Koene RA, Gerlag PG, Jansen JL et al. . Successful haemodialysis and renal transplantation in a patient with haemophilia A. Proc Eur Dial Transplant Assoc 1977;14:401–6. - PubMed
    1. Winter PC, Egan H, McNulty O et al. . A recurrent F8 mutation in Irish haemophilia A patients: evidence for a founder effect. Haemophilia 2008;14:394–5. 10.1111/j.1365-2516.2007.01639.x - DOI - PubMed
    1. The Renal Association UK Renal Registry. The Fifteenth Annual Report December 2012.
    1. Hadjianastassiou VG, Johnson RJ, Rudge CJ et al. . 2509 living donor nephrectomies, morbidity and mortality, including the UK introduction of laparoscopic donor surgery. Am J Transplant 2007;7:2532–7. 10.1111/j.1600-6143.2007.01975.x - DOI - PubMed

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