Associations between frequency of coffee consumption and osteoporosis in Chinese postmenopausal women

Abstract

Background: This study was aimed at estimating the associations between coffee intake and osteoporosis (OP) in Chinese postmenopausal women.

Methods: We conducted a large-scale, community-based, cross-sectional study to investigate the associations by using self-report questionnaire to access frequency of coffee intake. The total of 1817 participants was available to data analysis in this study. Multiple regression models controlling for confounding factors to include frequency of coffee intake variable were performed to investigate the relationships for OP.

Results: Positive correlations between frequency of meat food intake and T-score were reported (β = 0.216, P value < 0.001). Multiple regression analysis indicated that the frequency of meat food intake was significantly associated with OP (P < 0.05 for model 1 and model 2). The postmenopausal women with high frequency of meat food intake had a lower prevalence of OP.

Conclusion: The findings indicated that frequency of coffee intake was independently and significantly associated with OP. The prevalence of OP was more frequent in Chinese postmenopausal women not preferring coffee habits.

Keywords: Chinese postmenopausal women; Frequency; association; coffee intake; osteoporosis.

Figure 1

Comparison of T score among groups according to frequency of coffee intake. A. The results of comparison of T-score among groups according to Model 1 (Model 1: frequency of coffee intake were categorized by group 1: seldom, group 2: sometimes, group 3: always). The mean T-score was -1.91, -1.62 and -1.52 in the three groups, respectively. There were significantly differences among the three groups (P value < 0.001). B. The results of comparison of T-score between groups according to Model 2 (Model 2: frequency of coffee intake were categorized by low frequency and high frequency groups). The mean T-score was -1.91 and -1.57 in the two groups, respectively. There were no significantly differences between the two groups (P value < 0.001).

Figure 2

Comparison of prevalence of osteoporosis among groups according to frequency of coffee intake. A. The results of comparison of prevalence of osteoporosis among groups according to Model 1 (Model 1: frequency of coffee intake were categorized by group 1: seldom, group 2: sometimes, group 3: always). The prevalence of osteoporosis was 30.66%, 12.04% and 16.84% in the three groups, respectively. There were significantly differences among the three groups (P value < 0.001). B. The results of comparison of prevalence of osteoporosis between groups according to Model 2 (Model 2: frequency of coffee intake were categorized by low frequency and high frequency groups). The prevalence of osteoporosis was 30.66% and 14.29% between the two groups, respectively. There were significantly differences between the two groups (P value < 0.001).