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Editorial
. 2016 Jun;42(6):1051-4.
doi: 10.1007/s00134-015-4161-y. Epub 2015 Dec 2.

Is this critically ill patient immunocompromised?

Frédéric Pène  1   2 , Peter Pickkers  3 , Richard S Hotchkiss  4
Affiliations
Editorial

Is this critically ill patient immunocompromised?

Frédéric Pène et al. Intensive Care Med. 2016 Jun.

Erratum in

No abstract available

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
ARDS adult respiratory distress syndrome, IL-3 interleukin-3, GM-CSF granulocyte macrophage colony stimulating factor, IL-7 interleukin-7, anti-PD-1/PD-L1 anti-programmed cell death-1/programmed cell death ligand-1, IFN-γ interferon gamma
See this image and copyright information in PMC

References

    1. Hotchkiss RS, Karl IE. The pathophysiology and treatment of sepsis. N Engl J Med. 2003;348:138–150. doi: 10.1056/NEJMra021333. - DOI - PubMed
    1. Leentjens J, Kox M, van der Hoeven JG, Netea MG, Pickkers P. Immunotherapy for the adjunctive treatment of sepsis: from immunosuppression to immunostimulation. Time for a paradigm change? Am J Respir Crit Care Med. 2013;187:1287–1293. doi: 10.1164/rccm.201301-0036CP. - DOI - PubMed
    1. Daviaud F, Grimaldi D, Dechartres A, Charpentier J, Geri G, Marin N, Chiche JD, Cariou A, Mira JP, Pene F. Timing and causes of death in septic shock. Ann Intensive Care. 2015;5:58. doi: 10.1186/s13613-015-0058-8. - DOI - PMC - PubMed
    1. Petersen L, Andersen PK, Sorensen TI. Genetic influences on incidence and case-fatality of infectious disease. PLoS One. 2010;5:e10603. doi: 10.1371/journal.pone.0010603. - DOI - PMC - PubMed
    1. Saeed S, Quintin J, Kerstens HH, Rao NA, Aghajanirefah A, Matarese F, Cheng SC, Ratter J, Berentsen K, van der Ent MA, Sharifi N, Janssen-Megens EM, Ter Huurne M, Mandoli A, van Schaik T, Ng A, Burden F, Downes K, Frontini M, Kumar V, Giamarellos-Bourboulis EJ, Ouwehand WH, van der Meer JW, Joosten LA, Wijmenga C, Martens JH, Xavier RJ, Logie C, Netea MG, Stunnenberg HG. Epigenetic programming of monocyte-to-macrophage differentiation and trained innate immunity. Science. 2014;345:1251086. doi: 10.1126/science.1251086. - DOI - PMC - PubMed

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