Night-time blood pressure: a role in the prediction and prevention of diabetes?
- PMID: 26631216
- DOI: 10.1007/s00125-015-3814-2
Night-time blood pressure: a role in the prediction and prevention of diabetes?
Abstract
This commentary discusses and reviews the implications of two studies published in this issue of Diabetologia by Hermida et al (DOIs: 10.1007/s00125-015-3748-8 and 10.1007/s00125-015-3749-7 ) suggesting that high nocturnal blood pressure could have a role in the prediction of diabetes and act as a therapeutic target to prevent diabetes. This overview addresses the clinical implications of this work and new research that is likely to advance this field. It also provides a framework for interpreting claims of causality from observational studies and clinical trials.
Keywords: Antihypertensive therapy; Chronobiology; Hypertension; Prediction; Prevention; Type 2 diabetes.
Comment in
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Elevated asleep BP as predictor of type 2 diabetes and therapeutic target for prevention.Diabetologia. 2016 Feb;59(2):392-4. doi: 10.1007/s00125-015-3833-z. Epub 2015 Dec 7. Diabetologia. 2016. PMID: 26643878 No abstract available.
Comment on
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Sleep-time BP: prognostic marker of type 2 diabetes and therapeutic target for prevention.Diabetologia. 2016 Feb;59(2):244-54. doi: 10.1007/s00125-015-3748-8. Epub 2015 Sep 23. Diabetologia. 2016. PMID: 26399403
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Bedtime ingestion of hypertension medications reduces the risk of new-onset type 2 diabetes: a randomised controlled trial.Diabetologia. 2016 Feb;59(2):255-65. doi: 10.1007/s00125-015-3749-7. Epub 2015 Sep 23. Diabetologia. 2016. PMID: 26399404 Clinical Trial.
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