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Review
. 2015:2015:265260.
doi: 10.1155/2015/265260. Epub 2015 Oct 26.

New Insights in the Diagnosis and Treatment of Heart Failure

Giulio Agnetti  1 , Massimo F Piepoli  2 , Giuseppe Siniscalchi  3 , Francesco Nicolini  4
Affiliations
Review

New Insights in the Diagnosis and Treatment of Heart Failure

Giulio Agnetti et al. Biomed Res Int. 2015.

Abstract

Cardiovascular disease is the leading cause of mortality in the US and in westernized countries with ischemic heart disease accounting for the majority of these deaths. Paradoxically, the improvements in the medical and surgical treatments of acute coronary syndrome are leading to an increasing number of "survivors" who are then developing heart failure. Despite considerable advances in its management, the gold standard for the treatment of end-stage heart failure patients remains heart transplantation. Nevertheless, this procedure can be offered only to a small percentage of patients who could benefit from a new heart due to the limited availability of donor organs. The aim of this review is to evaluate the safety and efficacy of innovative approaches in the diagnosis and treatment of patients refractory to standard medical therapy and excluded from cardiac transplantation lists.

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Figures

Figure 1
Figure 1
(a) Acorn CorCap Cardiac Support Device. (b) Myosplint system. (c) Parachute ventricular partitioning device.
Figure 2
Figure 2
(a) Pulsatile pump. (b) Continuous flow pump.
Figure 3
Figure 3
Four different methods to weave Nitinol. From left to right: (a) Nitinol woven on PTFE with a solid U-shaped structure; (b) Nitinol woven on Kevlar in a circular manner; (c) Nitinol woven around a carbon-tube structure fixed on a Kevlar envelope; (d) silicon matrix with carbon tubes and Nitinol weaning weaving.
Figure 4
Figure 4
Ventricular “envelope” with a Nitinol woven structure on both sides.
Figure 5
Figure 5
Wires around the ventricle with a slice of PTFE between the wall and the wires.
See this image and copyright information in PMC

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