Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2015:2015:579-83.
doi: 10.1182/asheducation-2015.1.579.

Molecularly targeted therapies for acute myeloid leukemia

Eytan M Stein  1
Affiliations
Review

Molecularly targeted therapies for acute myeloid leukemia

Eytan M Stein. Hematology Am Soc Hematol Educ Program. 2015.

Abstract

The past 15 years have seen major leaps in our understanding of the molecular genetic mutations that act as drivers of acute myeloid leukemia (AML). Clinical trials of agents against specific mutant proteins, such as FLT3-internal tandem duplications (ITDs) and isocitrate dehydrogenase mutations (IDHs) are ongoing. This review discusses agents in clinical trials that target specific gene mutations and/or epigenetic targets.

PubMed Disclaimer

MeSH terms

LinkOut - more resources