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Meta-Analysis
. 2015:2015:762820.
doi: 10.1155/2015/762820. Epub 2015 Nov 10.

Prevalence of Hyperuricemia and Gout in Mainland China from 2000 to 2014: A Systematic Review and Meta-Analysis

Rui Liu  1 , Cheng Han  1 , Di Wu  1 , Xinghai Xia  1 , Jianqiu Gu  1 , Haixia Guan  1 , Zhongyan Shan  1 , Weiping Teng  1
Affiliations
Meta-Analysis

Prevalence of Hyperuricemia and Gout in Mainland China from 2000 to 2014: A Systematic Review and Meta-Analysis

Rui Liu et al. Biomed Res Int. 2015.

Abstract

We systematically identified the prevalence of hyperuricemia and gout in mainland China and provided informative data that can be used to create appropriate local public health policies. Relevant articles from 2000 to 2014 were identified by searching 5 electronic databases: PubMed, Google Scholar, Chinese Wanfang, CNKI, and Chongqing VIP. All of the calculations were performed using the Stata 11.0 and SPSS 20.0 software. The eligible articles (n = 36; 3 in English and 33 in Chinese) included 44 studies (38 regarding hyperuricemia and 6 regarding gout). The pooled prevalence of hyperuricemia and gout was 13.3% (95% CI: 11.9%, 14.6%) and 1.1% (95% CI: 0.7%, 1.5%), respectively. Although publication bias was observed, the results did not change after a trim and fill test, indicating that that impact of this bias was likely insignificant. The prevalence of hyperuricemia and gout was high in mainland China. The subgroup analysis suggested that the geographical region, whether the residents dwell in urban or rural and coastal or inland areas, the economic level, and sex may be associated with prevalence.

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Figures

Figure 1
Figure 1
Flow diagram for the literature-search process.
Figure 2
Figure 2
Forest plot of the pooled prevalence of hyperuricemia in mainland China.
Figure 3
Figure 3
Forest plot of the pooled prevalence of gout in mainland China.
Figure 4
Figure 4
Regional distribution of pooled prevalence of hyperuricemia in mainland China.
Figure 5
Figure 5
Regional distribution of pooled prevalence of gout in mainland China.
See this image and copyright information in PMC

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