A case of methanol poisoning leading to prolonged respirator dependency with consequent blindness and irreversible brain damage
- PMID: 26644889
- PMCID: PMC4650797
A case of methanol poisoning leading to prolonged respirator dependency with consequent blindness and irreversible brain damage
Abstract
Background: Methanol is a colorless and poisonous liquid that is commonly used as an industrial and household solvent. Methanol poisoning is a rare but extremely hazardous form of in toxication that affects the central nervous system and causes visual disorder, drowsiness, seizures and coma.
Case presentation: A 29-years-old man with methanol intoxication presented with drowsiness and acidosis with subsequent brain hemorrhage requiring prolong mechanical ventilation resulted in persistent visual impairment and disequilibrium.
Conclusion: Prolonged mechanical ventilation in patients with methanol intoxication may be assouated with irreversible brain damage.
Keywords: Brain hemorrhage; Mechanical ventilation; Methanol intoxication; Vision loss.
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References
-
- Taheri MS, Moghaddam HH, Moharamzad Y, Dadgari S, Nahvi V. The value of brain CT findings in acute methanol toxicity. Eur J Radiol. 2010;73:211–4. - PubMed
-
- Arora V, Nijjar IB, Multani AS, et al. MRI findings in methanol intoxication: a report of two cases. Br J Radiol. 2007;80:e243–6. - PubMed
-
- Bhatia R, Kumar M, Garg A, Nanda A. Putaminal necrosis due to methanol toxicity. Pract Neurol. 2008;8:386–7. - PubMed
-
- Karanjia N, Nordquist D, Stevens R, Nyquist P. A clinical description of extubation failure in patients with primary brain injury. Neurocrit Care. 2011;15:4–12. - PubMed
-
- Eskandar N, Apostolakos MJ. Weaning from mechanical ventilation. Crit Care Clin. 2007;23:263–74. - PubMed
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