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Randomized Controlled Trial
. 2016;45(2):20150224.
doi: 10.1259/dmfr.20150224. Epub 2015 Dec 9.

Neurosensoric disturbances after surgical removal of the mandibular third molar based on either panoramic imaging or cone beam CT scanning: A randomized controlled trial (RCT)

Lars B Petersen  1 , Michael Vaeth  2 , Ann Wenzel  1
Affiliations
Randomized Controlled Trial

Neurosensoric disturbances after surgical removal of the mandibular third molar based on either panoramic imaging or cone beam CT scanning: A randomized controlled trial (RCT)

Lars B Petersen et al. Dentomaxillofac Radiol. 2016.

Abstract

Objective: Pre-surgical CBCT has been suggested before removal of the mandibular third molar. Currently, the standard-of-care is two-dimensional (2D) panoramic imaging. The aim of this randomized controlled trial was to analyse possible differences in neurosensoric disturbances of the inferior alveolar nerve between patients undergoing either panoramic imaging or CBCT before surgical removal of the mandibular third molar. Furthermore, the aim was to perform a sensitivity analysis to assess the statistical significance of different assumptions related to sample size calculations.

Methods: 230 patients were randomized to a scan group and a non-scan group. All patients were referred from practicing dentists in the Copenhagen area. Inclusion criteria were overlap of the root complex and the mandibular canal on a 2D radiographic image. Central allocation of the randomization code and double blind settings were established. The surgical removal was performed in a specialized surgical practice geographically and personally separated from the study practice. Registration of neurosensoric anomalies was performed with a Semmes-Weinstein test and a visual analogue scale questionnaire pre- and post-surgically.

Results: In the scan group (n = 114), 21 episodes of neurosensoric disturbances were registered and in the non-scan group (n = 116), 13 episodes of neurosensoric disturbances were registered. There was no statistically significant difference between the two groups (p = 0.14). Performing a sensitivity analysis confirmed that CBCT was not superior to panoramic imaging in avoiding neurosensoric disturbances.

Conclusions: The use of CBCT before removal of the mandibular third molar does not seem to reduce the number of neurosensoric disturbances.

Keywords: CBCT scanning; mandibular third molar; neurosensoric disturbances; surgical removal.

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Figures

Figure 1
Figure 1
Flow chart of invited and enrolled participants in the study.
Figure 2
Figure 2
Study workflow.
Figure 3
Figure 3
Sensitivity analysis.
See this image and copyright information in PMC

References

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