Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2015 Sep;10(3):389-97.
doi: 10.5114/wiitm.2015.54187. Epub 2015 Sep 16.

Dynamics of quality of life improvement after floppy Nissen fundoplication for gastroesophageal reflux disease

Jarek Kobiela  1 , Łukasz Kaska  1 , Magdalena Pindel  1 , Arkadiusz Szarmach  2 , Maria Janiak  3 , Monika Proczko-Markuszewska  1 , Tomasz Stefaniak  1 , Dariusz Łaski  1 , Andrzej Łachiński  1 , Zbigniew Śledziński  1
Affiliations

Dynamics of quality of life improvement after floppy Nissen fundoplication for gastroesophageal reflux disease

Jarek Kobiela et al. Wideochir Inne Tech Maloinwazyjne. 2015 Sep.

Abstract

Introduction: Gastroesophageal reflux disease (GERD) has a negative impact on global quality of life (QOL) of patients. In patients affected by GERD, laparoscopic Nissen fundoplication is one of the most commonly performed laparoscopic procedures worldwide.

Aim: To prospectively analyze the dynamics of QOL as well as severity of pain in patients with GERD, before and after laparoscopic floppy Nissen fundoplication.

Material and methods: The study involved 104 consecutive patients operated on for GERD in whom laparoscopic floppy Nissen fundoplication was performed. QOL was assessed before surgery and 1, 3, 6, 12 and 24 months after. The following instruments were used: FACIT-G, FACIT-TS-G, GIQLI, GERD symptom scale.

Results: It was found that symptom relief and quality of life improvement presented different dynamics in the postoperative course. Observations revealed relief of symptoms 1 month after surgery and improvement in QOL related to the gastrointestinal tract and pain 3 months after surgery. Global QOL increased significantly as late as 12 months after surgery.

Conclusions: Gastroesophageal reflux disease is a chronic disease of long duration, leading to impairment of quality of life. Patients, apart from typical symptoms of GERD, suffer from pain of significant severity. QOL improves significantly after surgery. Surgical treatment results in relief of GERD symptoms, which leads to gradual improvement of QOL.

Keywords: Nissen fundoplication; gastroesophageal reflux disease; quality of life.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Total score in DeMeester and Johnson GERD symptom scale. ANOVA p < 0.001. Posthoc p values given in table below graph
Figure 2
Figure 2
Total gastrointestinal quality of life (GIQLI) score. ANOVA p = 0.002. Post-hoc p values presented in table below graph
Figure 3
Figure 3
Total FACIT-G score. ANOVA p = 0.005. Post-hoc p values given in table below graph
Figure 4
Figure 4
FACIT-TS-G score at follow-up points. ANOVA p = 0.531. Post-hoc analysis – no significant differences. By definition treatment satisfaction was not measured before surgery
Figure 5
Figure 5
Schematic demonstration of dynamics of quality of life improvement (with pain and symptom relief) after laparoscopic floppy Nissen fundoplication
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Blomqvist A, Lonroth H, Dalenback J, Ruth M. Quality of life assessment after laparoscopic and open fundoplications. Scand J Gastroenterol. 1996;31:1052–8. - PubMed
    1. Prasad M, Rentz AM, Revicki DA. The impact of treatment for gastro-oesophageal reflux disease on health related quality of life. Pharmacoeconomics. 2003;21:769–90. - PubMed
    1. Woodcock SA, Watson DI, Lally C, et al. International Society for Disease of the Esophagus – Australasian Section. Quality of life following laparoscopic anterior 90 degrees versus Nissen fundoplication: results from a multicenter randomized trial. World J Surg. 2006;30:1856–63. - PubMed
    1. Kamolz T, Granderath FA, Pointner R. Does major depression in patients with gastroesophageal reflux disease affect the outcome of laparoscopic antireflux surgery? Surg Endosc. 2003;17:55–60. - PubMed
    1. Kalinowska E. Quality of life and personality disorders in patients after surgical treatment of esophageal reflux disease. Postępy Nauk Medycznych. 2007;10:430–8.

LinkOut - more resources