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. 2015 Dec 8:59:28610.
doi: 10.3402/fnr.v59.28610. eCollection 2015.

Effects of goat milk-based formula on development in weaned rats

Meihong Xu  1   2 , Liren Wei  1   2 , Zhiyong Dai  3 , Yanchun Zhang  3 , Yong Li  1   2 , Junbo Wang  1   4
Affiliations

Effects of goat milk-based formula on development in weaned rats

Meihong Xu et al. Food Nutr Res. .

Abstract

Objective: The aim of this article is to study the effect of goat milk-based formula (GMF) on development in weaned rats.

Methods: One hundred Sprague-Dawley rats were randomly divided into five groups: control, 20% cow milk-based formula (CMF), and 5%-GMF, 10%-GMF, and 20%-GMF groups.

Results: GMF did play an active role in accelerating body and femur length, but not body weight growth. Compared with the control, GMF had better cognitive, space, and locomotor activity. The level of IFN was increased in GMF groups, as well as the level of IL-2 and TNF was decreased in GMF groups.

Conclusion: These results indicate that GMF has an effect on development and immunity improvability in weaned rats.

Keywords: development; goat milk–based formula; immunity; infant formula.

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Figures

Fig. 1
Fig. 1
Effect of GMF on body weight and body length trends in Sprague-Dawley rats treated with different levels of GMF, shown by body weight (a, female; b, male) and body length (c, female; d, male). aStatistical significance: p<0.05, compared with control; bstatistical significance: p<0.05, compared with 20%-CMF; cstatistical significance: p<0.05, compared with 5%-GMF; dstatistical significance: p<0.05, compared with 10%-GMF. GMF: goat milk–based formula.
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